[HTML][HTML] Population pharmacokinetics of abrocitinib in healthy individuals and patients with psoriasis or atopic dermatitis

…, X Wang, L Fostvedt, H Valdez, T Nicholas - Clinical …, 2022 - Springer
Background and Objective Abrocitinib is a Janus kinase 1 inhibitor in development for the
treatment of atopic dermatitis (AD). This work characterized orally administered abrocitinib …

The biodistribution and pharmacokinetics of the oxime acetylcholinesterase reactivator RS194B in guinea pigs

MA Malfatti, HA Enright, AB Nicholas, EA Kuhn… - Chemico-biological …, 2017 - Elsevier
Organophosphorus-based (OP) nerve agents represent some of the most toxic substances
known to mankind. The current standard of care for exposure has changed very little in the …

[BOOK][B] The things most definite: Death and work in Ernest Hemingway's nonfiction works

NA Valdez - 2003 - search.proquest.com
Ernest Hemingway examines issues of death and work in his three major nonfiction works,
illuminating the ways in which the two function for and against one another in the life of a man…

Improved chemical synthesis, identification and evaluation of prospective centrally active oxime antidotes for the treatment of nerve agent exposure

…, A Subramanian, HA Enright, MA Malfatti, AB Nicholas… - Tetrahedron, 2023 - Elsevier
An improved method for the synthesis of hydroxyiminoacetamide-based oximes, compounds
rhat hold great promise as centrally-active nerve agent antidotes, is described. The method …

An evaluation of the A4 folder system in general practice

A Elliott, N Valdez, C Dempsey, P Cooper - … Journal of the Royal College of …, 1979 - bjgp.org
All 63 general practices known to have introduced the A4 folder system were asked to
complete questionnaires comparing A4 records with the traditional medical records envelope …

Population pharmacokinetic‐pharmacodynamic modelling of platelet time‐courses following administration of abrocitinib

…, L Fostvedt, H Valdez, T Nicholas - British Journal of …, 2022 - Wiley Online Library
Aims Abrocitinib is a selective Janus kinase 1 inhibitor for the treatment of moderate‐to‐severe
atopic dermatitis. Herein we describe the time‐course of drug‐induced platelet reduction …

[BOOK][B] Crying out in the wilderness: The rhetoric of American Puritanism in contemporary minority literature, film, and cyberculture

NA Valdez - 2008 - search.proquest.com
The legacy of American Puritanism continues to haunt contemporary US socioeconomic,
racial, technological and cultural realities through the deployment of rhetorical tropes, …

[PDF][PDF] TheRoyal College of General Practitioners

…, IR McWhinney, CW Buck, A Elliott, N Valdez… - ncbi.nlm.nih.gov
These and other centres may be used as required, subject to a minimum (and in some
centres a maximum) number of candidates. It may be necessary to limit the total numbers and …

Correction to: Population Pharmacokinetics of Abrocitinib in Healthy Individuals and Patients with Psoriasis or Atopic Dermatitis

…, X Wang, L Fostvedt, H Valdez, T Nicholas - Clinical …, 2022 - Springer
With the author (s)’decision to opt for Open Choice the copyright of the article changed on
28th January 2022 to© The Author (s) 2022 and the article is forthwith distributed under a …

[BOOK][B] Heterarchy, Political Economy, and the Ancient Maya: The Three Rivers Region of the East-central Yucatˆn Peninsula

VL Scarborough, F Valdez, NP Dunning - 2003 - books.google.com
The ancient Maya of the southern Yucat‡ n peninsula remain a mystery to many scholars
attempting to explain early complex societies. Their dispersed settlement patterns and land-…