Objective The relationship between adipose tissue fibrosis, adipocyte hypertrophy, and
preadipocyte hyperplasia in the context of obesity and the correlation of these tissue‐based …

Background: Previous studies demonstrated that coplanar polychlorinated biphenyls (PCBs)
promote proinflammatory gene expression in adipocytes. PCBs are highly lipophilic and …

Increased adipose tissue macrophages (ATMs) correlate with metabolic dysfunction in
humans and are causal in development of insulin resistance in mice. Recent bulk and single-cell …

Context: The role of the extracellular matrix (ECM) in regulating adipocyte metabolism in the
context of metabolic disease is poorly defined. Objective: The objective of this study was to …

Objective Expansion of visceral adipose tissue (VAT) and metabolic inflammation are
consequences of obesity and associated with type 2 diabetes (T2DM). Metabolically activated …

Background Coplanar polychlorinated biphenyls (PCBs) promote adipocyte inflammation
and impair glucose homeostasis in lean mice. The diabetes-promoting effects of lipophilic …

Dysfunctional visceral adipose tissue (VAT) in obesity is associated with type 2 diabetes (DM)
but underlying mechanisms remain unclear. Our objective in this discovery analysis was to …

Adipocytes promote progression of multiple cancers, but their role in pancreatic intraepithelial
neoplasia (PanIN) and ductal adenocarcinoma (PDAC) is poorly defined. Nutrient transfer …

Resveratrol (RSV) is a plant polyphenol that exhibits several favorable effects on glucose
homeostasis in adipocytes. Recent studies from our laboratory demonstrated that coplanar …

The adipose tissue extracellular matrix (ECM) regulates adipocyte cellular metabolism and
is altered in obesity and type 2 diabetes, but mechanisms underlying ECM-adipocyte …