The 2017 international classification of the Ehlers–Danlos syndromes

…, JM Bowen, AF Brady, NP Burrows… - American Journal of …, 2017 - Wiley Online Library
The Ehlers–Danlos syndromes (EDS) are a clinically and genetically heterogeneous group
of heritable connective tissue disorders (HCTDs) characterized by joint hypermobility, skin …

Ehlers–Danlos syndrome, classical type

JM Bowen, GJ Sobey, NP Burrows… - American Journal of …, 2017 - Wiley Online Library
Classical EDS is a heritable disorder of connective tissue. Patients are affected with joint
hypermobility, skin hyperextensibilty, and skin fragility leading to atrophic scarring and …

Using the 7-point checklist as a diagnostic aid for pigmented skin lesions in general practice: a diagnostic validation study

…, J Vasconcelos, PN Hall, NP Burrows… - British Journal of …, 2013 - bjgp.org
Background GPs need to recognise significant pigmented skin lesions, given rising UK
incidence rates for malignant melanoma. The 7-point checklist (7PCL) has been recommended …

Smoking related COPD and facial wrinkling: is there a common susceptibility?

…, WJ Loo, AD Tasker, NJ Screaton, NP Burrows… - Thorax, 2006 - thorax.bmj.com
Background: Cigarette smoking causes accelerated facial wrinkling and predisposes to chronic
obstructive pulmonary disease (COPD). However, it has long been recognised that there …

A single base mutation in COL5A2 causes Ehlers-Danlos syndrome type II.

…, JB Harrison, FM Pope, NP Burrows - Journal of medical …, 1998 - jmg.bmj.com
Ehlers-Danlos syndrome (EDS) is a heterogeneous group of connective tissue disorders.
Recently mutations have been found in the genes for type V collagen in a small number of …

[PDF][PDF] A point mutation in an intronic branch site results in aberrant splicing of COL5A1 and in Ehlers-Danlos syndrome type II in two British families

NP Burrows, AC Nicholls, AJ Richards… - The American Journal of …, 1998 - cell.com
Ehlers-Danlos syndrome (EDS) is a heterogeneous group of connective-tissue disorders
characterized by skin fragility, joint laxity, and skeletal deformities. Type V collagen appears to …

[HTML][HTML] Silk garments plus standard care compared with standard care for treating eczema in children: a randomised, controlled, observer-blind, pragmatic trial …

…, A Ahmed, HC Williams, T Dean, NP Burrows… - PLoS …, 2017 - journals.plos.org
Background The role of clothing in the management of eczema (also called atopic dermatitis
or atopic eczema) is poorly understood. This trial evaluated the effectiveness and cost-…

The gene encoding collagen α1 (V)(COL5A1) is linked to mixed Ehlers-Danlos syndrome type I/II

NP Burrows, AC Nicholls, JRW Yates… - Journal of investigative …, 1996 - Elsevier
The Ehlers-Danlos syndrome (EDS) is a heterogeneo US group of inherited connective tissue
disorders in which cutaneous fragility and ligamentous laxity often combine with vascular, …

[HTML][HTML] Randomised controlled trial of silk therapeutic garments for the management of atopic eczema in children: the CLOTHES trial.

…, A Ahmed, T Dean, NP Burrows… - Health Technology …, 2017 - ncbi.nlm.nih.gov
BACKGROUND Atopic eczema (AE) is a chronic, itchy, inflammatory skin condition that
affects the quality of life of children and their families. The role of specialist clothing in the …

[HTML][HTML] PTPN11 mosaicism causes a spectrum of pigmentary and vascular neurocutaneous disorders and predisposes to melanoma

…, C Cottrell, O Davies, E Baselga, NP Burrows… - Journal of Investigative …, 2023 - Elsevier
Phakomatosis pigmentovascularis is a diagnosis that denotes the coexistence of pigmentary
and vascular birthmarks of specific types, accompanied by variable multisystem involvement…