[HTML][HTML] Production of polyhydroxybutyrate (PHB) and factors impacting its chemical and mechanical characteristics
B McAdam, M Brennan Fournet, P McDonald… - Polymers, 2020 - mdpi.com
Plastic pollution is fueling the grave environmental threats currently facing humans, the
animal kingdom, and the planet. The pursuit of renewable resourced biodegradable materials …
animal kingdom, and the planet. The pursuit of renewable resourced biodegradable materials …
[HTML][HTML] Recent developments in targeting carbonic anhydrase IX for cancer therapeutics
PC McDonald, JY Winum, CT Supuran, S Dedhar - Oncotarget, 2012 - ncbi.nlm.nih.gov
Carbonic anhydrase IX (CAIX) is a hypoxia-inducible enzyme that is overexpressed by cancer
cells from many tumor types, and is a component of the pH regulatory system invoked by …
cells from many tumor types, and is a component of the pH regulatory system invoked by …
Integrin-linked kinase–essential roles in physiology and cancer biology
PC McDonald, AB Fielding… - Journal of cell …, 2008 - journals.biologists.com
… depletion of Rictor decreased the amount of Ser473(P)-Akt in the ILK complex; these data
suggest that Rictor facilitates the phosphorylation of Akt by ILK (McDonald et al., 2008). The …
suggest that Rictor facilitates the phosphorylation of Akt by ILK (McDonald et al., 2008). The …
[BOOK][B] Stars
R Dyer, P McDonald - 2019 - books.google.com
Through the intensive examination of films, magazines, advertising and critical texts, Dyer
analyses the historical, ideological and aesthetic significance of stars, changing the way we …
analyses the historical, ideological and aesthetic significance of stars, changing the way we …
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates
The reactive thiol in cysteine is used for coupling maleimide linkers in the generation of
antibody conjugates. To assess the impact of the conjugation site, we engineered cysteines into …
antibody conjugates. To assess the impact of the conjugation site, we engineered cysteines into …
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors
Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund… - Cancer research, 2011 - AACR
Carbonic anhydrase IX (CAIX) is a hypoxia and HIF-1–inducible protein that regulates intra-
and extracellular pH under hypoxic conditions and promotes tumor cell survival and …
and extracellular pH under hypoxic conditions and promotes tumor cell survival and …
Impact of the graphic Canadian warning labels on adult smoking behaviour
Objective: To assess the impact of graphic Canadian cigarette warning labels on current
adult smokers. Design: A random-digit-dial telephone survey was conducted with 616 adult …
adult smokers. Design: A random-digit-dial telephone survey was conducted with 616 adult …
Graphic Canadian cigarette warning labels and adverse outcomes: evidence from Canadian smokers
…, GT Fong, PW McDonald… - … journal of public …, 2004 - ajph.aphapublications.org
Objectives. We assessed the impact of graphic Canadian cigarette warning labels. Methods.
We used a longitudinal telephone survey of 616 adult smokers. Results. Approximately one …
We used a longitudinal telephone survey of 616 adult smokers. Results. Approximately one …
[BOOK][B] The star system: Hollywood's production of popular identities
P McDonald - 2000 - books.google.com
… Copyright © Paul McDonald 2000 The moral right of Paul McDonald to be identified as the
author of this work has been asserted in accordance with the Copyright, Designs and Patents …
author of this work has been asserted in accordance with the Copyright, Designs and Patents …
Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis
F Pacchiano, F Carta, PC McDonald… - Journal of medicinal …, 2011 - ACS Publications
A series of ureido-substituted benzenesulfonamides was prepared that showed a very
interesting profile for the inhibition of several human carbonic anhydrases (hCAs, EC 4.2.1.1), …
interesting profile for the inhibition of several human carbonic anhydrases (hCAs, EC 4.2.1.1), …