Sentinel lymph node biopsy in breast cancer: guidelines and pitfalls of lymphoscintigraphy and gamma probe detection

…, R Pijpers, EF Comans, PJ Van Diest… - Journal of the …, 1998 - journals.lww.com
Background: Sentinel node (SN) biopsy appears to offer an alternative to routine axillary lymph
node dissection (ALND) for staging patients with breast cancer. Various techniques have …

Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer

JMJ Piek, PJ Van Diest, RP Zweemer… - The Journal of …, 2001 - Wiley Online Library
The aim of this study was to investigate the occurrence of (pre)neoplastic lesions in overtly
normal Fallopian tubes from women predisposed to developing ovarian carcinoma. The …

Levels of hypoxia-inducible factor-1α during breast carcinogenesis

…, PJ van Diest, E van der Wall - Journal of the …, 2001 - academic.oup.com
Background: Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that regulates gene
expression in critical pathways involved in tumor growth and metastases. In this report, we …

Biologic Correlates of 18Fluorodeoxyglucose Uptake in Human Breast Cancer Measured by Positron Emission Tomography

…, P Van der Groep, PJ Van Diest… - Journal of Clinical …, 2002 - ascopubs.org
PURPOSE: Variable uptake of the glucose analog 18 fluorodeoxyglucose (FDG) has been
noticed in positron emission tomography (PET) studies of breast cancer patients, with low …

Breast cancer histopathology image analysis: A review

M Veta, JPW Pluim, PJ Van Diest… - IEEE transactions on …, 2014 - ieeexplore.ieee.org
This paper presents an overview of methods that have been proposed for the analysis of
breast cancer histopathology images. This research area has become particularly relevant with …

Levels of hypoxia‐inducible factor‐1α independently predict prognosis in patients with lymph node negative breast carcinoma

…, PJ Van Diest, E Van der Wall - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND Hypoxia‐inducible factor‐1 (HIF‐1) is a transcription factor that plays an
important role in tumor growth and metastasis by regulating energy metabolism and inducing …

An organoid platform for ovarian cancer captures intra-and interpatient heterogeneity

…, H Vrieling, MPG Vreeswijk, PJ van Diest… - Nature medicine, 2019 - nature.com
Ovarian cancer (OC) is a heterogeneous disease usually diagnosed at a late stage. Experimental
in vitro models that faithfully capture the hallmarks and tumor heterogeneity of OC are …

[HTML][HTML] Micrometastases or isolated tumor cells and the outcome of breast cancer

…, JAAM Van Dijck, GF Borm, PJ Van Diest… - … England Journal of …, 2009 - Mass Medical Soc
Background The association of isolated tumor cells and micrometastases in regional lymph
nodes with the clinical outcome of breast cancer is unclear. Methods We identified all …

[HTML][HTML] Supplemental MRI screening for women with extremely dense breast tissue

…, HJ de Koning, PJ van Diest… - … England Journal of …, 2019 - Mass Medical Soc
Background Extremely dense breast tissue is a risk factor for breast cancer and limits the
detection of cancer with mammography. Data are needed on the use of supplemental magnetic …

Assessment of algorithms for mitosis detection in breast cancer histopathology images

M Veta, PJ Van Diest, SM Willems, H Wang… - Medical image …, 2015 - Elsevier
… Author links open overlay panel Mitko Veta a , Paul J. van Diest b , Stefan M. Willems b ,
Haibo Wang c , Anant Madabhushi c , Angel Cruz-Roa d , Fabio Gonzalez d , Anders BL Larsen …