Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity

…, R Ahmed, H Zhang, P Tombleson… - Human molecular …, 2020 - academic.oup.com
Using three European and two Chinese genome-wide association studies (GWAS), we
investigated the performance of genetic risk scores (GRSs) for predicting the susceptibility and …

[HTML][HTML] COVID-19 and systemic lupus erythematosus genetics: A balance between autoimmune disease risk and protection against infection

…, K Wu, Z Khaw, K Tzoumkas, P Tombleson… - PLoS …, 2022 - journals.plos.org
Genome wide association studies show there is a genetic component to severe COVID-19.
We find evidence that the genome-wide genetic association signal with severe COVID-19 is …

Variants in the DDX6-CXCR5 autoimmune disease risk locus influence the regulatory network in immune cells and salivary gland

…, C Sjowall, K Skarstein, KE Taylor, P Tombleson… - bioRxiv, 2023 - biorxiv.org
Fine mapping and bioinformatic analysis of the DDX6-CXCR5 genetic risk association in
Sjogrens Disease (SjD) and Systemic Lupus Erythematosus (SLE) identified five common …

Why do trainees take the MRCGP examination?

P Tombleson, R Wakeford - The Journal of the Royal College of …, 1989 - ncbi.nlm.nih.gov
12. Shroff KJ, Corrigan AM, Bosher M, et al. Cervical screening in an inner city area: response
to a call system in general practice. Br Med J 1988; 297: 1317. 13. Barley S. Primary …

Management of chronic (post-viral) fatigue syndrome

P TOMBLESON, R WAKEFORD - Journal of the Royal College of …, 1989 - ncbi.nlm.nih.gov
Sir, The contribution of Wessely and colleagues (January Journal, p. 26) to the management
of chronic (post-viral) fatigue syndrome, while disclaiming any'a priori assumption as to …

Genetic risk loadings influence the susceptibility and severity of systemic lupus erythematosus

L Chen, P Tombleson, A Bielowka, CA Odhams… - bioRxiv, 2019 - biorxiv.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of
clinical manifestations. Of these, kidney involvement is the most common cause of morbidity …

Countermovement jump height: Gender and sport-specific differences in the force-time variables

…, PP Wagner, TIL Tombleson - The Journal of Strength & …, 2014 - journals.lww.com
Laffaye, G, Wagner, PP, and Tombleson, TIL. Countermovement jump height: Gender and
sport-specific differences in the force-time variables. J Strength Cond Res 28 (4): 1096–1105, …

[PDF][PDF] Investigating the role of aberrant gene regulation in inflammatory bowel disease to understand pathogenesis and help predict relapse

SLJ Demandt - 2017 - kclpure.kcl.ac.uk
… Many thanks to the rest of the Complex Disease Group for making my time enjoyable: Phillip
Tombleson, for his never failing willingness to help, Yasmin Omar, for never letting us have …

Luminous blue variables are antisocial: their isolation implies that they are kicked mass gainers in binary evolution

N Smith, R Tombleson - Monthly Notices of the Royal …, 2015 - academic.oup.com
Based on their relatively isolated environments, we argue that luminous blue variables (LBVs)
must be primarily the product of binary evolution, challenging the traditional single-star …

Influence of familiarization and competitive level on the reliability of countermovement vertical jump kinetic and kinematic variables

ML Nibali, T Tombleson, PH Brady… - The Journal of Strength …, 2015 - journals.lww.com
Nibali, ML, Tombleson, T, Brady, PH, and Wagner, P. Influence of familiarization and competitive
level on the reliability of countermovement vertical jump kinetic and kinematic variables. …