Antibody responses to viral infections are sustained for decades by long-lived plasma cells (LLPCs).
However, LLPCs have yet to be characterized in humans. Here we used CD19, …

Objectives : The purpose of this study was to examine whether adding homocysteine (Hcy)
to a model based on traditional cardiovascular disease (CVD) risk factors improves risk …

Purpose Aurora A kinase (AAK) is overexpressed in aggressive lymphomas and can correlate
with more histologically aggressive forms of disease. We therefore designed a phase II …

Background Rituximab-hyper-CVAD alternating with rituximab-high-dose methotrexate and
cytarabine is a commonly utilized regimen in the United States for mantle cell lymphoma (…

Purpose Although rare overall, marginal zone B-cell lymphoma (MZBCL) is the most common
primary low-grade CNS lymphoma reported in the literature. The aim of this study is to …

The adaptive immune response is initiated by the interaction of T cell antigen receptors with
major histocompatibility complex molecule-peptide complexes in the nanometer scale gap …

Core needle biopsy (CNB) and fine-needle aspiration (FNA) are increasingly replacing
excisional lymph node biopsy in the diagnosis of lymphomas. However, evaluation of CNB and …

Recent data concerning scaffolding proteins profoundly challenge our conceptions of
multicomponent signal transduction systems. Recent studies of the phototransduction system in …

Recently, we demonstrated that IgG Abs can organize into ordered hexamers after binding
their cognate Ags expressed on cell surfaces. This process is dependent on Fc: Fc …

CD20 monoclonal antibody therapies have significantly improved the outlook for patients with
B-cell malignancies. However, many patients acquire resistance, demonstrating the need …