Eicosapentaenoic acid reduces rectal polyp number and size in familial adenomatous polyposis

…, SK Clark, RKS Phillips, JM Hutchinson, RJ Leicester… - Gut, 2010 - gut.bmj.com
Objective The omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) has
anticolorectal cancer activity in vitro and in preclinical models. The present study tested whether a …

Balsalazide is more effective and better tolerated than mesalamine in the treatment of acute ulcerative colitis

JRB Green, AJ Lobo, CD Holdsworth, RJ Leicester… - Gastroenterology, 1998 - Elsevier
Background & Aims: Aminosalicylates are widely used in the treatment of ulcerative colitis (UC).
Balsalazide is a novel mesalamine prodrug, activated by colonic bacteria. The aim of …

The low stapled anastomosis

RJ Heald, M Chir, RJ Leicester - Diseases of the Colon & Rectum, 1981 - journals.lww.com
… Heald RJ, Leicester RJ, The low stapled anastomosis. Dis Colon Rectum 1981:24:437-444. …
440 HEALD AND LEICESTER September t981 … Heald RJ. Towards fewer colostomies/the …

A prospective study of infrared coagulation, injection and rubber band ligation in the treatment of haemorrhoids

AJ Walker, RJ Leicester, RJ Nicholls… - International journal of …, 1990 - Springer
One hundred patients with non-prolapsing and one hundred with prolapsing haemorrhoids
were allocated to receive conventional treatment (CT) by injection sclerotherapy or rubber …

Colorectal cancer screening in Europe: differences in approach; similar barriers to overcome

…, W Fischbach, F Parente, RJ Leicester - International journal of …, 2009 - Springer
Worldwide diagnoses of bowel cancer approximate an estimated one million new cases per
year, comprising 9% of all cancer cases, and this has continued to increase over the last 25 …

Eicosapentaenoic acid (EPA) reduces crypt cell proliferation and increases apoptosis in normal colonic mucosa in subjects with a history of colorectal adenomas

…, A Belluzzi, E Roda, JY Kang, RJ Leicester - International journal of …, 2007 - Springer
Background and aims Omega-3 fatty acids in fish oil exert a protective effect on the development
of colorectal cancer in animal models. Patients with colorectal adenomas have been …

Chemoprevention of colorectal cancer

…, DM Melville, RJ Leicester - Alimentary …, 2004 - Wiley Online Library
Colorectal cancer is a disease with a high mortality at present, due to the late stage at which
many cases present. Attention is therefore focusing on preventative strategies for colorectal …

Guidelines for designing a digestive disease endoscopy unit: R eport of the W orld E ndoscopy O rganization

CJJ Mulder, MAJM Jacobs, RJ Leicester… - Digestive …, 2013 - Wiley Online Library
A dedicated digestive disease endoscopy unit is structurally and functionally differentiating
rapidly as a result of increasing diagnostic and therapeutic possibilities in the last 10–20 …

Infrared coagulation: a new treatment for hemorrhoids

RJ Leicester, R John Nicholls, CV Mann - Diseases of the Colon & …, 1981 - Springer
Many methods, which have effectively reduced the number of patients requiring hospital
admisssion, have been described for the outpatient treatment of hemorrhoids. However, …

Epidemic hypochlorhydria.

T Gledhill, RJ Leicester, B Addis, N Lightfoot… - Br Med J (Clin Res …, 1985 - bmj.com
During a study of gastric secretion four out of six previously healthy subjects developed
hypochlorhydria after a transient illness with nausea, vomiting, and abdominal pain. Mean basal …