User profiles for R. Fieldhouse
Robert FieldhousePostdoctoral fellow, Memorial Sloan Kettering Cancer Center & Harvard Medical School Verified email at cbio.mskcc.org Cited by 2467 |
[PDF][PDF] Comprehensive molecular portraits of invasive lobular breast cancer
Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive
breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, …
breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, …
A History of Modern British Adult Education.
R Fieldhouse - 1996 - ERIC
The purpose of this book is: to set the historical development of British adult education in its
wider policy and ideological context; to examine its various forms and formulations; and to …
wider policy and ideological context; to examine its various forms and formulations; and to …
Needle in the haystack: structure-based toxin discovery
RJ Fieldhouse, AR Merrill - Trends in biochemical sciences, 2008 - cell.com
In the current data-rich era, making the leap from sequence data to knowledge is a task that
requires an elegant bioinformatics toolset to pinpoint pressing research questions. Therefore…
requires an elegant bioinformatics toolset to pinpoint pressing research questions. Therefore…
Prevalence estimates of predicted pathogenic COL4A3–COL4A5 variants in a population sequencing database and their implications for Alport syndrome
Background The reported prevalence of Alport syndrome varies from one in 5000 to one in
53,000 individuals. This study estimated the frequencies of predicted pathogenic COL4A3–…
53,000 individuals. This study estimated the frequencies of predicted pathogenic COL4A3–…
[HTML][HTML] Cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae
The ADP-ribosyltransferases are a class of enzymes that display activity in a variety of
bacterial pathogens responsible for causing diseases in plants and animals, including those …
bacterial pathogens responsible for causing diseases in plants and animals, including those …
Catalytic asymmetric epoxidation of aldehydes. Optimization, mechanism, and discovery of stereoelectronic control involving a combination of anomeric and Cieplak …
…, H Adams, RVH Jones, R Fieldhouse - Journal of the …, 1998 - ACS Publications
… The presence of the thioacetal moiety enables the R and R‘ groups to be easily varied in order
… d By analogy we have assumed that the same absolute configuration (R,R) was obtained. …
… d By analogy we have assumed that the same absolute configuration (R,R) was obtained. …
Catalytic cyclopropanation of electron deficient alkenes mediated by chiral and achiral sulfides: scope and limitations in reactions involving phenyldiazomethane and …
…, G Hynd, RVH Jones, R Fieldhouse… - Journal of the …, 2000 - pubs.rsc.org
Phenyldiazomethane reacts with electron deficient alkenes in the presence of catalytic amounts
of transition metal catalyst [Rh2(OAc)4 was better than Cu(acac)2] and catalytic amounts …
of transition metal catalyst [Rh2(OAc)4 was better than Cu(acac)2] and catalytic amounts …
[HTML][HTML] A machine learning approach for hot-spot detection at protein-protein interfaces
R Melo, R Fieldhouse, A Melo, JDG Correia… - International journal of …, 2016 - mdpi.com
Understanding protein-protein interactions is a key challenge in biochemistry. In this work,
we describe a more accurate methodology to predict Hot-Spots (HS) in protein-protein …
we describe a more accurate methodology to predict Hot-Spots (HS) in protein-protein …
[HTML][HTML] C3larvin toxin, an ADP-ribosyltransferase from Paenibacillus larvae
D Krska, R Ravulapalli, RJ Fieldhouse, MR Lugo… - Journal of Biological …, 2015 - ASBMB
C3larvin toxin was identified by a bioinformatic strategy as a putative mono-ADP-ribosyltransferase
and a possible virulence factor from Paenibacillus larvae, which is the causative …
and a possible virulence factor from Paenibacillus larvae, which is the causative …
[HTML][HTML] Cholera-and anthrax-like toxins are among several new ADP-ribosyltransferases
RJ Fieldhouse, Z Turgeon, D White… - PLoS computational …, 2010 - journals.plos.org
Chelt, a cholera-like toxin from Vibrio cholerae, and Certhrax, an anthrax-like toxin from
Bacillus cereus, are among six new bacterial protein toxins we identified and characterized …
Bacillus cereus, are among six new bacterial protein toxins we identified and characterized …