A survey of adult patients was conducted in February 2006 to May 2006 in acute hospitals
across England, Wales, Northern Ireland and the Republic of Ireland to estimate the …

… Newcombe, RG ‘Interval estimation for the difference between independent proportions:
comparison of eleven methods’, Statistics in Medicine, 17, 873—890 (1998). 5. Newcombe, RG ‘…

… Newcombe, RG ‘Improved confidence interval methods for the difference between binomial
proportions based on paired data’, Submitted for publication. 20. Gart, JJ and Nam, JM. …

Background: Sentinel lymph node biopsy in women with operable breast cancer is routinely
used in some countries for staging the axilla despite limited data from randomized trials on …

Background Pulmonary rehabilitation seems to be an effective intervention in patients with
chronic obstructive pulmonary disease. We undertook a randomised controlled trial to assess …

… with border or signal intensity were calculated with CIs by using method 10 of Newcombe. …
were calculated with CIs by using method 10 of Newcombe ( , 15) and compared graphically ( …

Background The aim was to determine the accuracy of preoperative magnetic resonance
imaging (MRI) in the evaluation of pathological prognostic factors that influence local …

The relation between haemoglobin (Hb) concentrations at antenatal booking and subsequent
outcome was examined in 54 382 singleton pregnancies. Both high (greater than 13·2 g/dl…

Background Ulcerative colitis is largely a disease of nonsmokers. Because anecdotal
reports suggest that smoking and nicotine may improve the symptoms of the disease, we …

This study is the first large prospective RCT of sentinel node biopsy (SNB) compared with
standard axillary treatment (level I-III axillary lymph node dissection or four node sampling), …