Importance Sickle cell disease (SCD) is a life-threatening genetic disorder affecting nearly
100 000 individuals in the United States and is associated with many acute and chronic …

Sickle cell disease is a common and life-threatening haematological disorder that affects
millions of people worldwide. Abnormal sickle-shaped erythrocytes disrupt blood flow in small …

The primary clinical manifestations of paroxysmal nocturnal hemoglobinuria (PNH) are
hemolytic anemia, marrow failure, and thrombophilia. However, PNH is not a simple binary …

We present a new approach to remote sensing of water vapor based on the global positioning
system (GPS). Geodesists and geophysicists have devised methods for estimating the …

In the past two decades there has been an explosion of interest and intellectual activity in
industrial organization. Industrial organization was irreversibly transformed and rejuvenated by …

Background The acute chest syndrome is the leading cause of death among patients with
sickle cell disease. Since its cause is largely unknown, therapy is supportive. Pilot studies with …

Emerging networks of Global Positioning System (GPS) receivers can be used in the remote
sensing of atmospheric water vapor. The time-varying zenith wet delay observed at each …

This paper provides an overview of the methodology of and describes preliminary results
from an experiment called GPS/MET (Global Positioning System/Meteorology), in which …

… Comparisons of 11 representative temperature profiles derived from GPS/MET data with
nearby radiosonde and global analyses of temperatures are described by Ware et al. [1996]. …

Background Sickle-cell anaemia is associated with substantial morbidity from acute
complications and organ dysfunction beginning in the first year of life. Hydroxycarbamide …