User profiles for Rebecca Ward

Rebecca A Ward

Massachusetts General Hospital
Verified email at mgh.harvard.edu
Cited by 839

Single-molecule DNA sequencing of a viral genome

…, SR Quake, K Steinmann, E Thayer, A Tyurina, R Ward… - Science, 2008 - science.org
The full promise of human genomics will be realized only when the genomes of thousands of
individuals can be sequenced for comparative analysis. A reference sequence enables the …

Phase I study of STX 64 (667 Coumate) in breast cancer patients: the first study of a steroid sulfatase inhibitor

…, A Purohit, LWL Woo, S Sufi, D Vigushin, R Ward… - Clinical cancer …, 2006 - AACR
Purpose: Inhibition of steroid sulfatase (STS), the enzyme responsible for the hydrolysis of
steroid sulfates, represents a potential novel treatment for postmenopausal women with …

Cervical epidural steroid injection with intrinsic spinal cord damage: two case reports

SD Hodges, RL Castleberg, T Miller, R Ward… - Spine, 1998 - journals.lww.com
Study Design. Intrinsic cervical spinal cord damage represents the serious and permanent
complications that can occur if cervical epidural steroid injections are administered while the …

The CD4-gpl20 interaction and AIDS pathogenesis

DJ Capon, RHR Ward - Annual review of immunology, 1991 - annualreviews.org
Infection by the human immunodeficiency virus (HIV) leads to progressive destruction of the
CD4 T subset of T lymphocytes, resulting in immuno deficiency and AIDS. The selectivity of …

[HTML][HTML] An enhanced isothermal amplification assay for viral detection

…, JM Fajnzylber, RT Ingram, RH Ward… - Nature …, 2020 - nature.com
Rapid, inexpensive, robust diagnostics are essential to control the spread of infectious
diseases. Current state of the art diagnostics are highly sensitive and specific, but slow, and …

[HTML][HTML] Evolution combined with genomic study elucidates genetic bases of isobutanol tolerance in Escherichia coli

…, AB Veloso, B Xie, CA McConnell, RJ Ward… - Microbial cell …, 2011 - Springer
Background Isobutanol is a promising next-generation biofuel with demonstrated high yield
microbial production, but the toxicity of this molecule reduces fermentation volumetric …

[HTML][HTML] The absolute and relative risk of type 2 diabetes after gestational diabetes: a systematic review and meta-analysis of 129 studies

…, D Kotecha, G Farmer, SJ Sharp, RJ Ward… - Diabetes research and …, 2021 - Elsevier
Structured Abstract Aims To estimate development of type 2 diabetes (T2DM) in women with
previous gestational diabetes (GDM) and investigate characteristics associated with higher …

An investigation of byte n-gram features for malware classification

…, R Zak, R Cox, J Sylvester, P Yacci, R Ward… - Journal of Computer …, 2018 - Springer
Malware classification using machine learning algorithms is a difficult task, in part due to the
absence of strong natural features in raw executable binary files. Byte n-grams previously …

NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia

R Ward, W Li, Y Abdul, LD Jackson, G Dong… - Pharmacological …, 2019 - Elsevier
Diabetes increases the risk and worsens the progression of cognitive impairment via the
greater occurrence of small vessel disease and stroke. Yet, the underlying mechanisms are not …

Intrinsic visual-motor synchrony correlates with social deficits in autism

…, CA Nettles, KL Sweeney, K Ament, RE Ward… - Biological …, 2016 - Elsevier
Background Imitation, which is impaired in children with autism spectrum disorder (ASD)
and critically depends on the integration of visual input with motor output, likely impacts both …