Regulating the use of antibiotics in the community
C Carbon, RP Bax - Bmj, 1998 - bmj.com
The world market for antibiotics in 1997 was $17 bn (£ 10.6 bn), of which $12 bn was for
community use, with about 818 billion prescriptions for respiratory tract infections. Although the …
community use, with about 818 billion prescriptions for respiratory tract infections. Although the …
Antibiotic resistance: a view from the pharmaceutical industry
RP Bax - Clinical Infectious Diseases, 1997 - academic.oup.com
The development of new antibiotics has been successful in significantly reducing morbidity
and mortality. With increasing use there has occurred an increase in antibiotic resistance but …
and mortality. With increasing use there has occurred an increase in antibiotic resistance but …
Self-medication of antibacterials without prescription (also called 'over-the-counter'use) A report of a Working Party of the British Society for Antimicrobial …
DS Reeves, RG Finch, RP Bax… - Journal of …, 1999 - academic.oup.com
The availability of antimicrobial agents for self-medication may increase and could include
antibacterial agents for oral or topical use. Wholesale deregulation of antibacterials would be …
antibacterial agents for oral or topical use. Wholesale deregulation of antibacterials would be …
[PDF][PDF] Challenges in developing new antibacterial drugs
KJ Williams, RP Bax - Curr Opin Investig Drugs, 2009 - researchgate.net
Regulatory guidelines for clinical development of antibacterial drugs have a major impact
on decisions regarding research, infuencing the degree to which novel targets are pursued, …
on decisions regarding research, infuencing the degree to which novel targets are pursued, …
Role of Bax and Bak in mitochondrial morphogenesis
M Karbowski, KL Norris, MM Cleland, SY Jeong… - Nature, 2006 - nature.com
… cells Bax or Bak is required for normal fusion of mitochondria into elongated tubules. Bax
seems … Our results show that Bax and Bak regulate mitochondrial dynamics in healthy cells and …
seems … Our results show that Bax and Bak regulate mitochondrial dynamics in healthy cells and …
Bax regulates primary necrosis through mitochondrial dynamics
… Bax and Bak are the principal activators of MOMP and apoptosis. Unexpectedly, we find that
deletion of Bax … Triple knockout mice lacking Bax/Bak and cyclophilin D, a key regulator of …
deletion of Bax … Triple knockout mice lacking Bax/Bak and cyclophilin D, a key regulator of …
Small-molecule allosteric inhibitors of BAX
… BAX-mediated cell death in a host of diseases. Here, we describe a class of small-molecule
BAX … unrecognized pocket and allosterically inhibit BAX activation. BAI binding around the …
BAX … unrecognized pocket and allosterically inhibit BAX activation. BAI binding around the …
The multidomain proapoptotic molecules Bax and Bak are directly activated by heat
LJ Pagliari, T Kuwana, C Bonzon… - Proceedings of the …, 2005 - National Acad Sciences
… change, it may be possible to activate Bax and Bak independently of BH3-only proteins. …
Bax and Bak, resulting in oligomerization and activation. Cells and mitochondria lacking Bax …
Bax and Bak, resulting in oligomerization and activation. Cells and mitochondria lacking Bax …
THE APPEAL
RP BAX - europepmc.org
… RICHARD P. BAX 10 Sandy Lodge Way Northwood Middx. … Sir, In your April issue (p.
240)you summarize a paper by Rylance (Lancet, 1980, 2, 1099-1102) which hasmany …
240)you summarize a paper by Rylance (Lancet, 1980, 2, 1099-1102) which hasmany …
POLYMYALGIA RHEUMATICA
RP Bax - The Journal of the Royal College of General …, 1981 - ncbi.nlm.nih.gov
I also wondered why Dr Bull was so keen on pregnancy tests. He did not explain in his paper
what there was to be gained by a pregnancy test at six weeks over a clinical assessment at …
what there was to be gained by a pregnancy test at six weeks over a clinical assessment at …