We describe a framework for defining pilot and feasibility studies focusing on studies conducted
in preparation for a randomised controlled trial. To develop the framework, we undertook …

… We begin to examine these issues through the lens of “the Abilities” – the statement of
fundamental principles that guide ISOC’s work in terms of the capabilities we believe all Internet …

Background Lay‐led self‐management programmes are becoming widespread in the
attempt to promote self‐care for people with chronic conditions. Objectives To assess …

Assessment of risk of bias is regarded as an essential component of a systematic review on
the effects of an intervention. The most commonly used tool for randomised trials is the …

… Abstracts can follow different structures dependent on a journal’s style. They are typically
around 300 words. We outline what information should be reported in the abstract irrespective …

Retinal pigment epithelium (RPE) of 50 human eyes, five from each 10 decades of life, were
analyzed using ultrastructural morphometric techniques. Content of three types of pigments, …

… w18 Proposed frameworks have added an “implementation cycle” to complement the
MRC’s complex intervention cycle,13 or extended a linear spectrum (see fig 1⇓).Others have …

… The biodegradable polymers possess heteroatoms (O, N, S) distributed along the polymer
backbone that act as sites for hydrolytic or enzymatic reactions, leading to significant …

Background Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its
metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect of …

… These included a list of cluster randomized trials in primary care obtained from a systematic
review (S. Eldridge et al., unpublished data) (153 publications) and from manual searches of …