[HTML][HTML] Prevention of bleeding after cardiopulmonary bypass with high-dose tranexamic acid: double-blind, randomized clinical trial

JM Karski, SJ Teasdale, P Norman, J Carroll… - The Journal of thoracic …, 1995 - Elsevier
This prospective, double-blind, randomized trial assessed the effectiveness of high-dose
tranexamic acid given in the preoperative period on blood loss in patients undergoing …

The effect of three different doses of tranexamic acid on blood loss after cardiac surgery with mild systemic hypothermia (32° C)

…, C Peniston, K Bailey, MFX Glynn, SJ Teasdale… - Journal of cardiothoracic …, 1998 - Elsevier
Objective: Prophylactic administration of tranexamic acid (TA), an antifibrinolytic agent,
decreases bleeding after cardiac surgery with systemic hypothermia (25C to 29C). Warmer …

Prevention of postbypass bleeding with tranexamic acid and ϵ-aminocaproic acid

JM Karski, SJ Teasdale, PH Norman, JA Carroll… - Journal of cardiothoracic …, 1993 - Elsevier
In this institution, two antifibrinolytic agents have been in routine use before cardiopulmonary
bypass (CPB) to prevent bleeding due to fibrinolysis; ϵ-aminocaproic acid (EACA) or …

Hormonal and metabolic responses during coronary artery bypass surgery: role of infused glucose

MR WERB, B ZINMAN, SJ TEASDALE… - The Journal of …, 1989 - academic.oup.com
Anesthesia, surgery, and hypothermia are conventionally considered the major stress
factors in the metabolic and hormonal responses to cardiac surgery. We compared these …

The effect of warm heart surgery on postoperative bleeding

…, J Ivanov, Z Sun, R Yu, MFX Glynn, SJ Teasdale - The Journal of thoracic …, 1992 - Elsevier
The effects of normothermic systemic perfusion (35 to 37 C; n = 73) were compared with
those of moderately hypothermic systemic perfusion (25 to 29 C; n = 73) with respect to blood …

Pulmonary atelectasis and other respiratory complications after cardiopulmonary bypass and investigation of aetiological factors

GD Gale, SJ Teasdale, DE Sanders… - Canadian Anaesthetists' …, 1979 - Springer
Radiological evidence of pulmonary complications and possible aetiological factors were
investigated in 50 consecutive patients after heart operations with cardiopulmonary bypass. …

Effects of anaesthetic induction on myocardial function and metabolism: a comparison of fentanyl, sufentanil and alfentanil

DR Miller, M Wellwood, SJ Teasdale, D Laidley… - Canadian journal of …, 1988 - Springer
Anaesthetic induction may induce myocardial ischaemia. A prospective randomized trial
was instituted to compare the effect on ventricular function and myocardial metabolism of …

Limitations of blood conservation

…, SE Fremes, J Ivanov, DAG Mickle, SJ Teasdale… - The Journal of thoracic …, 1984 - Elsevier
Blood conservation has been most successful when blood salvage techniques have been
combined with postoperative normovolemic hemodilution. The hemodynamic and myocardial …

Ancrod (Arvin) as an alternative to heparin anticoagulation for cardiopulmonary bypass.

VJ Zulys, SJ Teasdale, ER Michel, RA Skala… - …, 1989 - europepmc.org
Heparin is the anticoagulant used during cardiopulmonary bypass (CPB). Both the use of
heparin and the reversal of its effect with protamine have well-documented complications. …

Effects of postoperative hypertension and its treatment

…, RJ Burns, SJ Teasdale, J Ivanov, SJ Seawright… - The Journal of thoracic …, 1983 - Elsevier
Hypertension following aorta-coronary bypass operations can contribute to myocardial
ischemia. Nitroprusside therapy will reduce afterload, preload, and coronary perfusion pressure. …