QT lengthening and life-threatening arrhythmias associated with fexofenadine.
PM Craig-McFeely, SL Freemantle… - The British Journal of …, 2000 - ncbi.nlm.nih.gov
Sir, Fexofenadine is the active metabolite of the non-sedating antihistamine, terfenadine.
Accumulation of terfenadine can cause prolongation of the QT interval and significant cardiac …
Accumulation of terfenadine can cause prolongation of the QT interval and significant cardiac …
Developmentally-related candidate retinoic acid target genes regulated early during neuronal differentiation of human embryonal carcinoma
SJ Freemantle, JS Kerley, SL Olsen, RH Gross… - Oncogene, 2002 - nature.com
Embryonal carcinoma is a model of embryonic development as well as tumor cell differentiation.
In response to all-trans retinoic acid (RA), the human embryonal carcinoma (EC) cell line…
In response to all-trans retinoic acid (RA), the human embryonal carcinoma (EC) cell line…
[HTML][HTML] Negative feedback at the level of nuclear receptor coregulation: self-limitation of retinoid signaling by RIP140
…, AV Vaseva, E Rieder, SJ Freemantle… - Journal of Biological …, 2003 - ASBMB
Nuclear receptor-mediated gene expression is proposed to be regulated by the ordered
recruitment of large protein complexes in which activity depends on mutual interactions and …
recruitment of large protein complexes in which activity depends on mutual interactions and …
A 4‐decade record of elevation change of the Amery Ice Shelf, East Antarctica
… relative to instantaneous sea level (SL) on 30 … SL connection was not found in the surviving
field notes. Personal diary entries (M. Corry, unpublished diary, 1968–1969) state that the SL …
field notes. Personal diary entries (M. Corry, unpublished diary, 1968–1969) state that the SL …
[HTML][HTML] Ethnic-specific normative reference values for echocardiographic LA and LV size, LV mass, and systolic function: the EchoNoRMAL study
…, RC Davis, A Roalfe, M Calvert, N Freemantle… - JACC: Cardiovascular …, 2015 - Elsevier
Objectives This study sought to derive age-, sex-, and ethnic-appropriate adult reference
values for left atrial (LA) and left ventricular (LV) dimensions and volumes, LV mass, fractional …
values for left atrial (LA) and left ventricular (LV) dimensions and volumes, LV mass, fractional …
[HTML][HTML] Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal …
LF Sempere, S Freemantle, I Pitha-Rowe, E Moss… - Genome biology, 2004 - Springer
Background The microRNAs (miRNAs) are an extensive class of small noncoding RNAs (18
to 25 nucleotides) with probable roles in the regulation of gene expression. In …
to 25 nucleotides) with probable roles in the regulation of gene expression. In …
Retinoids in cancer therapy and chemoprevention: promise meets resistance
SJ Freemantle, MJ Spinella, E Dmitrovsky - Oncogene, 2003 - nature.com
Retinoids (natural and synthetic derivatives of vitamin A) signal potent differentiation and
growth-suppressive effects in diverse normal, premalignant, and malignant cells. A strong …
growth-suppressive effects in diverse normal, premalignant, and malignant cells. A strong …
Prevalence of treatment resistance and clozapine use in early intervention services
… The data were analysed by IS, SLG and RUIS, SLG, RU and RJ drafted the manuscript, with
further input from MBIS and SL G. contributed jointly to the manuscript. All authors provided …
further input from MBIS and SL G. contributed jointly to the manuscript. All authors provided …
[HTML][HTML] Five-year illness trajectories across racial groups in the UK following a first episode psychosis
Purpose Psychosis disproportionally affects ethnic minority groups in high-income countries,
yet evidence of disparities in outcomes following intensive early intervention service (EIS) …
yet evidence of disparities in outcomes following intensive early intervention service (EIS) …
Transition state treatment of the relative viscosity of electrolytic solutions. Applications to aqueous, non-aqueous and methanol+ water systems
D Feakins, DJ Freemantle, KG Lawrence - Journal of the Chemical …, 1974 - pubs.rsc.org
A transition-state treatment of the relative viscosity of electrolyte solutions is described. The
following expression is found for the viscosity B-coefficient: B=(text-decoration:overlineV1–…
following expression is found for the viscosity B-coefficient: B=(text-decoration:overlineV1–…