Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants

…, KM Morabito, L Novik, S O'Connell, S O'Dell… - Science, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutations may diminish
vaccine-induced protective immune responses, particularly as antibody titers wane over time. …

Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial

…, F Castellino, B Flach, BC Lin, S O'Connell… - Science, 2022 - science.org
In the coronavirus efficacy (COVE) phase 3 clinical trial, vaccine recipients were assessed
for neutralizing and binding antibodies as correlates of risk for COVID-19 disease and as …

[HTML][HTML] Antibody persistence through 6 months after the second dose of mRNA-1273 vaccine for Covid-19

…, MS Suthar, M Makowski, S O'Connell… - … England Journal of …, 2021 - Mass Medical Soc
Persistence of Antibody after mRNA-1273 Vaccination A total of 33 participants who received
both doses of the Moderna mRNA-1273 vaccine against SARS-CoV-2 had blood drawn …

[HTML][HTML] Homologous and heterologous Covid-19 booster vaccinations

…, AB McDermott, SE O'Connell… - … England Journal of …, 2022 - Mass Medical Soc
Background Although the three vaccines against coronavirus disease 2019 (Covid-19) that
have received emergency use authorization in the United States are highly effective, …

[HTML][HTML] Evaluation of the mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates

…, AP Werner, B Flach, S O'Connell… - … England Journal of …, 2020 - Mass Medical Soc
Background Vaccines to prevent coronavirus disease 2019 (Covid-19) are urgently needed.
The effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines on …

Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

…, JS Dasen, SE Flynn, DJ Norman, SM O'Connell… - Nature, 1996 - nature.com
The gene apparently responsible for a heritable form of murine pituitary-dependent dwarfism
(Ames dwarf, df) has been positionally cloned, identifying a novel, tissue-specific, paired-…

[HTML][HTML] Lyme borreliosis: clinical case definitions for diagnosis and management in Europe

…, A Krause, W Kristoferitsch, S O'connell… - Clinical Microbiology …, 2011 - Elsevier
Lyme borreliosis, caused by spirochaetes of the Borrelia burgdorferigenospecies complex,
is the most commonly reported tick-borne infection in Europe and North America. The non-…

Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants

…, RD Mason, AF Nazzari, L Novik, S O'Connell, S O'Dell… - Science, 2021 - science.org
INTRODUCTION Worldwide appearance of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) variants of concern (VOCs) with increased transmissibility and resistance to …

Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates

KS Corbett, MC Nason, B Flach, M Gagne, S O'Connell… - Science, 2021 - science.org
INTRODUCTION Mass vaccination against severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) offers the most efficient public health intervention to control the COVID-19 …

Long-term nonsurgical management of Barrett's esophagus with high-grade dysplasia

…, SJ Sontag, G Chejfec, G Aranha, A Metz, S O'connell… - Gastroenterology, 2001 - Elsevier
Background & Aims: Surgical resection of the esophagus is frequently recommended for
Barrett's high-grade dysplasia (HGD) without cancer. Methods: During a 20-year period, …