Objective To determine the effect of home blood pressure monitoring on blood pressure
levels and proportion of people with essential hypertension achieving targets. Design Meta-…

Objective: To compare glycaemic control and insulin dosage in people with type 1 diabetes
treated by continuous subcutaneous insulin infusion (insulin infusion pump therapy) or …

Background Self-monitoring of blood pressure (BP) appears to reduce BP in hypertension
but important questions remain regarding effective implementation and which groups may …

In most randomised trials each subject is individually assigned at random to an intervention
group. The intervention is applied directly to the subject and observations are made on each …

Background Cluster randomized trials are increasingly popular. In many of these trials, cluster
sizes are unequal. This can affect trial power, but standard sample size formulae for these …

Hypertension and stroke are important threats to the health of adults in sub-Saharan Africa.
Nevertheless, detection of hypertension is haphazard and stroke prevention targets are …

Objective To determine whether screening and treating women for chlamydial infection
reduces the incidence of pelvic inflammatory disease over the subsequent 12 months. Design …

A meta-analysis was performed of the effect of 3hydroxy3methylglutaryl-coenzyme A reductase
inhibitors (statins) on blood pressure in humans including the randomized, controlled …

Cluster randomised trials are trials in which groups (or clusters) of individuals are randomly
allocated to different forms of treatment. In health care, these trials often compare different …

We have described the calculation of sample size when subjects are randomised in groups
or clusters in terms of two variances—the variance of observations taken from individuals in …