Simple Summary When tumors become resistant to chemotherapeutics, alternative treatment
strategies must be explored. Gene targeting provides a personalized and molecular …

Muscle development in childhood and muscle regeneration in adults are highly regulated
processes that are necessary for reaching and maintaining optimal muscle mass and strength …

Gene regulation resulting from glucocorticoid receptor and glucocorticoid response element
interactions is a hallmark feature of stress response signaling. Imbalanced glucocorticoid …

Skeletal muscle differentiation and regeneration are regulated by interactions between
exogenous hormone- and growth factor-activated signaling cascades and endogenous muscle-…

The GnRH receptor is a G protein-coupled receptor (GPCR), and its ligand GnRH is the central
regulator of the reproductive system. GnRH receptors are known to target a wide variety …

Fatty acyl-Coenzyme A species (acyl-CoAs) are key biomarkers in studies focusing on cellular
energy metabolism. Existing analytical approaches are unable to simultaneously detect …

The p38 MAP kinases play critical roles in skeletal muscle biology, but the specific processes
regulated by these kinases remain poorly defined. Here we find that activity of p38α/β is …

Mutations in the nucleocapsid of SARS-CoV-2 may interfere with antigen detection by
diagnostic tests. We used several methods to evaluate the effect of various SARS-CoV-2 …

In states with universal mandatory reporting of child abuse and neglect (CAN), it is essential
that people who work with children and youth in a community be appropriately trained to …

The binding of GnRH to its receptor on pituitary gonadotropes leads to the targeting of a
diverse array of signalling mediators. These mediators drive multiple signal transduction …