User profiles for Sarah Wordsworth

Sarah Wordsworth, PhD

University of Oxford
Verified email at dph.ox.ac.uk
Cited by 9932

[HTML][HTML] Are whole-exome and whole-genome sequencing approaches cost-effective? A systematic review of the literature

K Schwarze, J Buchanan, JC Taylor, S Wordsworth - Genetics in Medicine, 2018 - Elsevier
Purpose We conducted a systematic literature review to summarize the current health economic
evidence for whole-exome sequencing (WES) and whole-genome sequencing (WGS). …

[HTML][HTML] Economic methods for valuing the outcomes of genetic testing: beyond cost-effectiveness analysis

SD Grosse, S Wordsworth, K Payne - Genetics in Medicine, 2008 - nature.com
Genetic testing in health care can provide information to help with disease prediction,
diagnosis, prognosis, and treatment. Assessing the clinical utility of genetic testing requires a …

[BOOK][B] Applied methods of cost-effectiveness analysis in healthcare

AM Gray, PM Clarke, JL Wolstenholme, S Wordsworth - 2010 - books.google.com
The third volume in the Handbooks in Health Economic Evaluation series, this book provides
the reader with a comprehensive set of instructions and examples of how to perform an …

Ranibizumab versus bevacizumab to treat neovascular age-related macular degeneration: one-year findings from the IVAN randomized trial

…, CA Rogers, SM Downes, AJ Lotery, S Wordsworth… - Ophthalmology, 2012 - Elsevier
PURPOSE: To compare the efficacy and safety of ranibizumab and bevacizumab intravitreal
injections to treat neovascular age-related macular degeneration (nAMD). DESIGN: …

[HTML][HTML] Liberal or restrictive transfusion after cardiac surgery

…, K Pike, CA Rogers, S Wordsworth… - … England Journal of …, 2015 - Mass Medical Soc
Background Whether a restrictive threshold for hemoglobin level in red-cell transfusions, as
compared with a liberal threshold, reduces postoperative morbidity and health care costs …

Effect of a strategy of a supraglottic airway device vs tracheal intubation during out-of-hospital cardiac arrest on functional outcome: the AIRWAYS-2 randomized …

…, EA Stokes, J Taylor, M Thomas, S Voss, S Wordsworth… - Jama, 2018 - jamanetwork.com
Importance The optimal approach to airway management during out-of-hospital cardiac
arrest is unknown. Objective To determine whether a supraglottic airway device (SGA) is …

The challenge of antimicrobial resistance: what economics can contribute

…, PS Tan, AS Walker, JV Robotham, S Wordsworth - Science, 2019 - science.org
BACKGROUND Antimicrobial resistance (AMR) is increasing, driven by widespread antibiotic
use. The wide availability of effective antibiotics is under threat, jeopardizing modern …

[HTML][HTML] Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study

…, P Tang, MH Wilcox, S Wordsworth… - The Lancet …, 2016 - thelancet.com
Background Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis
complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome …

Video-assisted thoracoscopic or open lobectomy in early-stage lung cancer

…, P De Sousa, EA Stokes, S Wordsworth… - NEJM …, 2022 - evidence.nejm.org
Background There is limited randomized evidence on the comparative outcomes of early-stage
lung cancer resection by video-assisted thoracoscopic surgery (VATS) versus open …

[HTML][HTML] The complete costs of genome sequencing: a microcosting study in cancer and rare diseases from a single center in the United Kingdom

…, AT Pagnamenta, A Schuh, JC Taylor, S Wordsworth - Genetics in …, 2020 - Elsevier
Purpose The translation of genome sequencing into routine health care has been slow, partly
because of concerns about affordability. The aspirational cost of sequencing a genome is …