User profiles for Sarah Wordsworth
Sarah Wordsworth, PhDUniversity of Oxford Verified email at dph.ox.ac.uk Cited by 9932 |
[HTML][HTML] Are whole-exome and whole-genome sequencing approaches cost-effective? A systematic review of the literature
Purpose We conducted a systematic literature review to summarize the current health economic
evidence for whole-exome sequencing (WES) and whole-genome sequencing (WGS). …
evidence for whole-exome sequencing (WES) and whole-genome sequencing (WGS). …
[HTML][HTML] Economic methods for valuing the outcomes of genetic testing: beyond cost-effectiveness analysis
SD Grosse, S Wordsworth, K Payne - Genetics in Medicine, 2008 - nature.com
Genetic testing in health care can provide information to help with disease prediction,
diagnosis, prognosis, and treatment. Assessing the clinical utility of genetic testing requires a …
diagnosis, prognosis, and treatment. Assessing the clinical utility of genetic testing requires a …
[BOOK][B] Applied methods of cost-effectiveness analysis in healthcare
The third volume in the Handbooks in Health Economic Evaluation series, this book provides
the reader with a comprehensive set of instructions and examples of how to perform an …
the reader with a comprehensive set of instructions and examples of how to perform an …
Ranibizumab versus bevacizumab to treat neovascular age-related macular degeneration: one-year findings from the IVAN randomized trial
PURPOSE: To compare the efficacy and safety of ranibizumab and bevacizumab intravitreal
injections to treat neovascular age-related macular degeneration (nAMD). DESIGN: …
injections to treat neovascular age-related macular degeneration (nAMD). DESIGN: …
[HTML][HTML] Liberal or restrictive transfusion after cardiac surgery
Background Whether a restrictive threshold for hemoglobin level in red-cell transfusions, as
compared with a liberal threshold, reduces postoperative morbidity and health care costs …
compared with a liberal threshold, reduces postoperative morbidity and health care costs …
Effect of a strategy of a supraglottic airway device vs tracheal intubation during out-of-hospital cardiac arrest on functional outcome: the AIRWAYS-2 randomized …
Importance The optimal approach to airway management during out-of-hospital cardiac
arrest is unknown. Objective To determine whether a supraglottic airway device (SGA) is …
arrest is unknown. Objective To determine whether a supraglottic airway device (SGA) is …
The challenge of antimicrobial resistance: what economics can contribute
BACKGROUND Antimicrobial resistance (AMR) is increasing, driven by widespread antibiotic
use. The wide availability of effective antibiotics is under threat, jeopardizing modern …
use. The wide availability of effective antibiotics is under threat, jeopardizing modern …
[HTML][HTML] Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
…, P Tang, MH Wilcox, S Wordsworth… - The Lancet …, 2016 - thelancet.com
Background Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis
complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome …
complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome …
Video-assisted thoracoscopic or open lobectomy in early-stage lung cancer
…, P De Sousa, EA Stokes, S Wordsworth… - NEJM …, 2022 - evidence.nejm.org
Background There is limited randomized evidence on the comparative outcomes of early-stage
lung cancer resection by video-assisted thoracoscopic surgery (VATS) versus open …
lung cancer resection by video-assisted thoracoscopic surgery (VATS) versus open …
[HTML][HTML] The complete costs of genome sequencing: a microcosting study in cancer and rare diseases from a single center in the United Kingdom
Purpose The translation of genome sequencing into routine health care has been slow, partly
because of concerns about affordability. The aspirational cost of sequencing a genome is …
because of concerns about affordability. The aspirational cost of sequencing a genome is …