Unbiased next-generation sequencing (NGS) approaches enable comprehensive pathogen
detection in the clinical microbiology laboratory and have numerous applications for public …

Background. Encephalitis continues to result in substantial morbidity and mortality
worldwide. Advances in diagnosis and management have been limited, in part, by a lack of …

In the United States, during the past half-century, the number of humans to die of rabies
dramatically decreased to an average of 1–2 per year. Although the number of deaths is low, …

To the Editor: During the 2001 anthrax outbreak, we evaluated and validated a highly sensitive
and specific three-target (two plasmid and one chromosomally located target) 5 nuclease …

Rocky Mountain spotted fever (RMSF) is a life-threatening tick-borne disease documented
in North, Central, and South America. In California, RMSF is rare; nonetheless, recent fatal …

Recent phylogenetic analyses of cetacean relationships based on DNA sequence data
have challenged the traditional view that baleen whales (Mysticeti) and toothed whales (…

Background Enterovirus D68 was implicated in a widespread outbreak of severe respiratory
illness across the USA in 2014 and has also been reported sporadically in patients with …

The evolution of virulence was studied in a virus subjected to alternating episodes of
vertical and horizontal transmission. Bacteriophage f1 was used as the parasite because it …

Rhinovirus is a respiratory virus most typically associated with the common cold and asthma
exacerbations, and has not traditionally been considered to play a major role in severe …

Rabies was undetected in terrestrial wildlife of northern Arizona until 2001, when rabies was
diagnosed in 19 rabid skunks in Flagstaff. Laboratory analyses showed causative rabies …