Background: Treatment of moderate or severe chronic obstructive pulmonary disease (COPD)
with combinations of inhaled corticosteroids, long-acting β-agonists, and long-acting …

Background: It is unclear whether asthma is overdiagnosed in developed countries, particularly
among obese individuals, who may be more likely than nonobese people to experience …

Importance Although asthma is a chronic disease, the expected rate of spontaneous
remissions of adult asthma and the stability of diagnosis are unknown. Objective To determine …

Background Endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA)
of mediastinal lymph nodes has been found to be more accurate than standard TBNA in …

Background We performed systematic reviews using the population, intervention, comparison,
outcome (PICO) format to answer the following key clinical question: Are the CHEST 2006 …

Mycobacterium avium complex (MAC) is ubiquitous. It is found in various freshwater and
saltwater sources around the world, including hot water pipes. Although the organism was …

Background Unexplained chronic cough (UCC) causes significant impairments in quality of
life. Effective assessment and treatment approaches are needed for UCC. Methods This …

Study objective To determine the prevalences of symptomatic gastroesophageal reflux (GER),
reflux-associated respiratory symptoms (RARS), and reflux-associated β-agonist inhaler …

Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive myelinated
sensory nerves play essential roles in regulating cough. These vagal sensory nerves …

Rationale: Improved therapeutic options are needed for patients with treatment-refractory
nontuberculous mycobacterial lung disease caused by Mycobacterium avium complex (MAC). …