Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has undergone progressive
change, with variants conferring advantage rapidly becoming dominant lineages, eg, B.…

The race to produce vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
began when the first sequence was published, and this forms the basis for …

Terminating the SARS-CoV-2 pandemic relies upon pan-global vaccination. Current
vaccines elicit neutralizing antibody responses to the virus spike derived from early isolates. …

SARS-CoV-2 has caused over 2 million deaths in little over a year. Vaccines are being
deployed at scale, aiming to generate responses against the virus spike. The scale of the …

Comprehensive multiplatform analysis of 80 uveal melanomas (UM) identifies four molecularly
distinct, clinically relevant subtypes: two associated with poor-prognosis monosomy 3 (M3…

A review of some of the steps the Bureau of Labor Statistics has taken to integrate the
computer with its schedule screening processes is presented. The underlying principles which …

This randomized phase 3 clinical trial evaluated the potential benefit of the addition of
gemtuzumab ozogamicin (GO) to standard induction and postconsolidation therapy in patients …

Large uncertainties in the budget of atmospheric methane (CH 4 ) limit the accuracy of
climate change projections. Here we describe and quantify an important source of CH 4 —point-…

Crystallization remains a critical step in X-ray structure determination. Because it is not
generally possible to rationally predict crystallization conditions, commercial screens have been …

Enterovirus 71 (EV71) is a major agent of hand, foot and mouth disease in children that can
cause severe central nervous system disease and death. No vaccine or antiviral therapy is …