Background Alzheimer's disease and its complications are the leading cause of death in
adults with Down syndrome. Studies have assessed Alzheimer's disease in individuals with …

Introduction Adults with Down syndrome (DS) invariably develop Alzheimer's disease (AD)
neuropathology. Understanding amyloid deposition in DS can yield crucial information about …

Individuals with Down syndrome (DS) are more likely to experience earlier onset of multiple
facets of physiological aging. This includes brain atrophy, beta amyloid deposition, cognitive …

This paper argues that strategic voting in young democracies increases as voters become
more experienced with the functioning of democracy. This proposition is tested with election …

… Dr Annus reported being a current employee at Johnson & Johnson. Dr Lehmann reported
receiving personal fees for service on the scientific advisory boards of Roche Diagnostics …

People with Down syndrome (DS) have a neurodevelopmentally distinct brain and invariably
developed amyloid neuropathology by age 50. This cross-sectional study aimed to provide …

… in the regulatory T-cell function. In several autoimmune diseases, CD4 + CD25 + regulatory
T-cells (Tregs) from peripheral blood were found to have a poor capacity to suppress T-cell …

Down's syndrome is a chromosomal disorder that invariably results in both intellectual disability
and Alzheimer's disease neuropathology. However, only a limited number of studies to …

… frame of reference which rotates with Beff(t) called the ‘Beff frame’ … resultant magnetic field
E(t) is the vector sum of Beff(t) and … For simplicity, let the B1(t) and (t) functions be such that Beff …

Cardiovascular diseases are the most prevalent cause of morbidity and mortality among
patients with type 1 or type 2 diabetes. The proposed mechanisms that can link accelerated …