User profiles for T. Griffin

Timothy M Griffin

Aging and Metabolism Research Program, Oklahoma Medical Research Foundation
Verified email at omrf.org
Cited by 5396

Self-expanding metallic stents for relieving malignant colorectal obstruction: a systematic review

AM Watt, IG Faragher, TT Griffin, NA Rieger… - Annals of …, 2007 - journals.lww.com
Objective: To assess the safety and efficacy of self-expanding metallic stents (SEMS) placement
for the relief of malignant colorectal obstruction in comparison to surgical procedures …

[HTML][HTML] Oxidative stress and covalent modification of protein with bioactive aldehydes

PA Grimsrud, H Xie, TJ Griffin, DA Bernlohr - Journal of Biological …, 2008 - ASBMB
The term "oxidative stress" links the production of reactive oxygen species to a variety of
metabolic outcomes, including insulin resistance, immune dysfunction, and inflammation. …

The role of mechanical loading in the onset and progression of osteoarthritis

TM Griffin, F Guilak - Exercise and sport sciences reviews, 2005 - journals.lww.com
Osteoarthritis (OA) is a progressive joint disease characterized by varying degrees of pain
and degeneration. The disease affects the structural and functional integrity of articular …

[HTML][HTML] Abiraterone in metastatic prostate cancer without previous chemotherapy

…, ME Taplin, Y Park, T Kheoh, T Griffin… - … England Journal of …, 2013 - Mass Medical Soc
Background Abiraterone acetate, an androgen biosynthesis inhibitor, improves overall
survival in patients with metastatic castration-resistant prostate cancer after chemotherapy. We …

Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302) …

…, P de Souza, JS de Bono, TW Griffin… - The Lancet …, 2015 - thelancet.com
Background Abiraterone acetate plus prednisone significantly improved radiographic
progression-free survival compared with placebo plus prednisone in men with chemotherapy-…

Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on …

…, M Glogauer, M Goldstein, TJ Griffin… - Journal of …, 2018 - Wiley Online Library
Periodontal health is defined by absence of clinically detectable inflammation. There is a
biological level of immune surveillance that is consistent with clinical gingival health and …

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

EV Haar, S Lee, S Bandhakavi, TJ Griffin, DH Kim - Nature cell biology, 2007 - nature.com
Insulin stimulates protein synthesis and cell growth by activation of the protein kinases Akt (also
known as protein kinase B, PKB) and mammalian target of rapamycin (mTOR). It was …

2016 classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American …

…, YJ Gao, T Griffin, S Hashad, T Hennon… - Arthritis & …, 2016 - Wiley Online Library
Objective To develop criteria for the classification of macrophage activation syndrome (MAS)
in patients with systemic juvenile idiopathic arthritis (JIA). Methods A multistep process, …

Gender matters, too: the influences of school racial discrimination and racial identity on academic engagement outcomes among African American adolescents.

…, D Rivas-Drake, C Smalls, T Griffin… - Developmental …, 2008 - psycnet.apa.org
The authors examined relationships among racial identity, school-based racial discrimination
experiences, and academic engagement outcomes for adolescent boys and girls in …

[HTML][HTML] Complementary profiling of gene expression at the transcriptome and proteome levels in saccharomyces cerevisiae* S

TJ Griffin, SP Gygi, T Ideker, B Rist, J Eng… - Molecular & Cellular …, 2002 - ASBMB
Using an integrated genomic and proteomic approach, we have investigated the effects of
carbon source perturbation on steady-state gene expression in the yeast Saccharomyces …