User profiles for T. Madden
Thomas L. MaddenStaff Scientist, NCBI, NLM, NIH Verified email at ncbi.nlm.nih.gov Cited by 143212 |
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
… to be raised substantially while retaining comparable sensitivity—from T = 11 to T = 13 for
the one-hit heuristic. (The two-hit heuristic described above lowers T back to 11.) As will be …
the one-hit heuristic. (The two-hit heuristic described above lowers T back to 11.) As will be …
[HTML][HTML] Database resources of the national center for biotechnology information
The National Center for Biotechnology Information (NCBI) provides a large suite of online
resources for biological information and data, including the GenBank® nucleic acid sequence …
resources for biological information and data, including the GenBank® nucleic acid sequence …
Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements
… Let T be total number of true positives available to be found. For a fixed number of false
positives n, the quantity ROC n is the proportion of the area in the rectangle [0,T][0,… Here T is total …
positives n, the quantity ROC n is the proportion of the area in the rectangle [0,T][0,… Here T is total …
Database resources of the national center for biotechnology information
In addition to maintaining the GenBank® nucleic acid sequence database, the National
Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the …
Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the …
Database resources of the national center for biotechnology information
…, D Landsman, DJ Lipman, TL Madden… - Nucleic acids …, 2007 - academic.oup.com
In addition to maintaining the GenBank(R) nucleic acid sequence database, the National
Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the …
Center for Biotechnology Information (NCBI) provides analysis and retrieval resources for the …
[HTML][HTML] BLAST+: architecture and applications
…, N Ma, J Papadopoulos, K Bealer, TL Madden - BMC …, 2009 - Springer
… Figure 2 presents the speedup for these searches, with speedup defined as (T baseline /T
blastx ) - 1. Query splitting decreases the search time for queries longer than 20 kbases, and …
blastx ) - 1. Query splitting decreases the search time for queries longer than 20 kbases, and …
Prediction of goal-directed behavior: Attitudes, intentions, and perceived behavioral control
I Ajzen, TJ Madden - Journal of experimental social psychology, 1986 - Elsevier
… At the time of Wave 2, respondents had significantly lowered their expectations to an average
grade of 4.26 (t(S9) = 3.62, p c .Ol); 38% now expected to get an “A,” 48% a “B,” and 14% a …
grade of 4.26 (t(S9) = 3.62, p c .Ol); 38% now expected to get an “A,” 48% a “B,” and 14% a …
BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences
TA Tatusova, TL Madden - FEMS microbiology letters, 1999 - academic.oup.com
‘BLAST 2 Sequences’, a new BLAST-based tool for aligning two protein or nucleotide
sequences, is described. While the standard BLAST program is widely used to search for …
sequences, is described. While the standard BLAST program is widely used to search for …
[HTML][HTML] Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction
… These databases are non-redundant as they don’t have the same sequence regions covered
more than once, thus allowing better specificity checking. They are the databases of choice …
more than once, thus allowing better specificity checking. They are the databases of choice …
NCBI BLAST: a better web interface
…, Y Merezhuk, S McGinnis, TL Madden - Nucleic acids …, 2008 - academic.oup.com
Basic Local Alignment Search Tool (BLAST) is a sequence similarity search program. The
public interface of BLAST, http://www.ncbi.nlm.nih.gov/blast, at the NCBI website has recently …
public interface of BLAST, http://www.ncbi.nlm.nih.gov/blast, at the NCBI website has recently …