[HTML][HTML] Mechanisms of ATP release in pain: role of pannexin and connexin channels

MF Muñoz, TN Griffith, JE Contreras - Purinergic signalling, 2021 - Springer
Pain is a physiological response to bodily damage and serves as a warning of potential threat.
Pain can also transform from an acute response to noxious stimuli to a chronic condition …

[PDF][PDF] Juneteenth in STEMM and the barriers to equitable science

…, S Andrisse, S Townsend, SM Damo, TN Griffith… - Cell, 2023 - cell.com
We are 52 Black scientists. Here, we establish the context of Juneteenth in STEMM and
discuss the barriers Black scientists face, the struggles they endure, and the lack of recognition …

NaV1. 1 is essential for proprioceptive signaling and motor behaviors

…, KM Wells, DA O'neil, KA Wilkinson, TN Griffith - Elife, 2022 - elifesciences.org
… Jorge Contreras and Ioana Carcea for sharing behavioral equipment, Miguel Gonzalez
Fernandez for writing code to automate ex vivo data analysis, and members of the Griffith

The mechanisms of cold encoding

CM Lewis, TN Griffith - Current Opinion in Neurobiology, 2022 - Elsevier
Cold sensation is initiated in the periphery by a specialized population of cold-sensitive
neurons, referred to as cold receptors, who transmit decreases in temperature with sub-degree …

Tetrodotoxin-sensitive sodium channels mediate action potential firing and excitability in menthol-sensitive Vglut3-lineage sensory neurons

TN Griffith, TA Docter, EA Lumpkin - Journal of Neuroscience, 2019 - Soc Neuroscience
Small-diameter vesicular glutamate transporter 3-lineage (Vglut3 lineage ) dorsal root ganglion
(DRG) neurons play an important role in mechanosensation and thermal hypersensitivity…

Computational design of peptides to target NaV1. 7 channel with high potency and selectivity for the treatment of pain

…, A Ghetti, MW Pennington, B Hammock, TN Griffith… - Biophysical journal, 2023 - cell.com
1Department of Physiology and Membrane Biology, University of California Davis, Davis, CA,
USA, 2Department of Pharmacology, University of California Davis, Davis, CA, USA, …

Identification of critical functional determinants of kainate receptor modulation by auxiliary protein Neto2

TN Griffith, GT Swanson - The Journal of Physiology, 2015 - Wiley Online Library
Identification of critical functional determinants of kainate receptor modulation by auxiliary
protein Neto2 - Griffith - 2015 - The Journal of Physiology - Wiley Online Library …

[HTML][HTML] Coordinated nuclear and synaptic shuttling of afadin promotes spine plasticity and histone modifications

…, I Rafalovich, K Sellers, KA Jones, TN Griffith… - Journal of Biological …, 2014 - ASBMB
The ability of a neuron to transduce extracellular signals into long lasting changes in neuronal
morphology is central to its normal function. Increasing evidence shows that coordinated …

[HTML][HTML] Thermal escape box: A cost-benefit evaluation paradigm for investigating thermosensation and thermal pain

…, AK Romo, YJ Chen, JE Contreras, TN Griffith - Neurobiology of Pain, 2024 - Elsevier
Griffith has assigned a provisional patent to the University of California related to the described
… Thanks to members of the Griffith and Contreras laboratories for helpful discussions. …

Cyclohexanol analogues are positive modulators of GABAA receptor currents and act as general anaesthetics in vivo

AC Hall, TN Griffith, M Tsikolia, FO Kotey, N Gill… - European journal of …, 2011 - Elsevier
GABA A receptors meet all the pharmacological criteria required to be considered important
general anaesthetic targets. In the following study, the modulatory effects of various …