BMD and clinical risk factors predict hip and other osteoporotic fractures. The combination
of clinical risk factors and BMD provide higher specificity and sensitivity than either alone. …

Since its inception in the mid-1980s, the General Practice Research Database (GPRD) has
undergone many changes but remains the largest validated and most utilised primary care …

Background and aims: The objective of this study was to evaluate the risk of colorectal cancer
(CRC) in patients taking aminosalicylates (5-ASA) for inflammatory bowel disease (IBD). …

Background Computerised databases of primary care clinical records are widely used for
epidemiological research. In Catalonia, the Information System for the Development of …

Objectives: The goal of comparative effectiveness analysis is to examine the relationship
between two variables, treatment, or exposure and effectiveness or outcome. Unlike data …

A population‐based British cohort study, including ∼6% of the population, was used to derive
age‐ and sex‐specific incidence rates of fractures during childhood. Fractures were more …

The Clinical Practice Research Datalink (CPRD) is an ongoing primary care database of
anonymised medical records from general practitioners, with coverage of over 11.3 million …

Administration of oral corticosteroids is associated with the development of osteoporosis and
an increased risk of fractures. However, the size of the treated sub‐population who would …

Atrial fibrillation (AF) carries an increased risk of ischaemic stroke, and oral anticoagulation
with warfarin can reduce this risk. The objective of this study was to evaluate the association …

Rates of fracture worldwide are changing. Using the Clinical Practice Research Datalink (CPRD),
age, and gender, geographical, ethnic and socioeconomic trends in fracture rates …