Background Some heroin addicts persistently fail to benefit from conventional treatments.
We aimed to compare the effectiveness of supervised injectable treatment with medicinal …

… Tom Carnwath has an establishment background, studying medicine at Cambridge and
then in London. He worked as a GP briefly before training as a psychiatrist. He has the usual …

This study compares the clinical response to lofexidine and clonidine in the out-patient treatment
of opiate withdrawal in 50 opiate addicts, using a randomised double-blind study design…

Despite decades of research, the mechanism of Parkinson’s disease pathogenesis remains
unclear. Studies have focused heavily on the protein α-synuclein, which is the primary …

A significant minority of 1990s youth are drinking more alcohol, smoking more tobacco and/or
using more illicit drugs despite a decade of major political and policy initiatives ranging …

Aims The R andomized I njectable O pioid T reatment T rial ( RIOTT) compared supervised
injectable heroin ( SIH ) and supervised injectable methadone ( SIM ) with optimized oral …

Aim To determine the scale and practice of diamorphine (heroin) prescribing for opiate
dependence in the United Kingdom in 2000. Design Postal survey. Setting England, Scotland …

Patients with a severe mental illness such as schizophrenia have significant rates of
concurrent amphetamine use. Such dual diagnosis patients have been shown to have poorer …

We investigated the impact of hepatitis C testing on injecting risk behaviour reported by opiate
using injecting drug users (IDUs). Semi-structured interviews and focus group discussions …

Two cases of zolpidem tolerance and dependence are reported. The literature is reviewed
for other reported cases, and the potential for abuse of zolpidem is discussed.