Fatal lymphocytic cardiac damage in coronavirus disease 2019 (COVID‐19): autopsy reveals a ferroptosis signature

…, M Mergeay, S Sirimsi, V Matheeussen… - ESC heart …, 2020 - Wiley Online Library
Aims Cardiovascular complications, including myocarditis, are observed in coronavirus
disease 2019 (COVID‐19). Major cardiac involvement is a potentially lethal feature in severe …

Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial

…, MD de Jong, JT Connor, V Matheeussen… - The Lancet, 2020 - thelancet.com
Background Antivirals are infrequently prescribed in European primary care for influenza-like
illness, mostly because of perceived ineffectiveness in real world primary care and …

DPP4 inhibition improves functional outcome after renal ischemia-reperfusion injury

…, A Verhulst, V Matheeussen… - American Journal …, 2012 - journals.physiology.org
Dipeptidyl peptidase 4 (DPP4) is an exopeptidase which modulates the function of its
substrates, among which are insulin-releasing incretins. DPP4 inhibitors are currently used to …

Dipeptidyl peptidase IV inhibition improves cardiorenal function in overpacing‐induced heart failure

N Gomez, K Touihri, V Matheeussen… - European journal of …, 2012 - Wiley Online Library
Aims Recent studies indicate that brain natriuretic peptide (BNP 1–32 ) may be truncated
into BNP 3–32 by dipeptidyl peptidase IV (DPP4) and that BNP 3–32 has reduced biological …

[HTML][HTML] Comparison of commercial realtime reverse transcription PCR assays for the detection of SARS-CoV-2

…, ZAK Abou-Nouar, B Weller, V Matheeussen… - Journal of Clinical …, 2020 - Elsevier
The emergence of a new coronavirus in Wuhan China has triggered a global need for accurate
diagnostic assays. Initially, mostly laboratory developed molecular tests were available …

[HTML][HTML] International external quality assessment for SARS-CoV-2 molecular detection and survey on clinical laboratory preparedness during the COVID-19 …

V Matheeussen, VM Corman, OD Mantke… - …, 2020 - eurosurveillance.org
Laboratory preparedness with quality-assured diagnostic assays is essential for controlling
the current coronavirus disease (COVID-19) outbreak. We conducted an external quality …

Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors

V Matheeussen, AM Lambeir, W Jungraithmayr… - Clinica chimica acta, 2012 - Elsevier
BACKGROUND: Dipeptidyl peptidase IV (DPPIV, DPP4) is a serine protease that releases N-terminal
dipeptides. It is a validated drug target for type 2 diabetes and DPPIV inhibitors are …

Left ventricular diastolic dysfunction and myocardial stiffness in diabetic mice is attenuated by inhibition of dipeptidyl peptidase 4

…, L Vandekerckhove, V Matheeussen… - Cardiovascular …, 2014 - academic.oup.com
Aims Obesity and Type 2 diabetes mellitus (DM) induce left ventricular (LV) diastolic
dysfunction, which contributes to an increasing prevalence of heart failure with a preserved LV …

[HTML][HTML] Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages

…, KL Nielsen, N Frimodt-Møller, V Matheeussen… - Nature …, 2020 - nature.com
Escherichia coli is the leading cause of urinary tract infection, one of the most common
bacterial infections in humans. Despite this, a genomic perspective is lacking regarding the …

[HTML][HTML] Increase in bloodstream infections caused by emm1 group A Streptococcus correlates with emergence of toxigenic M1UK, Belgium, May 2022 to August 2023

…, S van Kleef-van Koeveringe, V Matheeussen… - …, 2023 - eurosurveillance.org
Many European countries have recently reported upsurges in invasive group A Streptococcus
(iGAS) infections, mainly caused by emm1 Streptococcus pyogenes, specifically the …