Background The COVID-19 pandemic has altered the context for antimicrobial stewardship
in primary care. Aim To assess the effect of the pandemic on antibiotic prescribing, …

Background There is substantial variation in the use of urgent suspected cancer referral (2-week
wait [2WW]) between practices. Aim To examine the change in use of 2WW referrals in …

Delivering lung cancer care during the COVID-19 pandemic has posed significant and
ongoing challenges. There is a lack of published COVID-19 and lung cancer evidence-based …

Background Antibiotic use can have negative unintended consequences including disruption
of the human microbiota, which is thought to protect against pathogen overgrowth. We …

Introduction Ideally, health conditions causing the greatest global disease burden should
attract increased research attention. We conducted a comprehensive global study investigating …

Objectives: To assess cognition in populations born and living at high altitude (HA; 3,700 m)
and low altitude (LA; 500 m) in Bolivia, who were similar for both socioeconomic status and …

Study Objectives: To compare polysomnographic parameters in high altitude (HA) native
Andean children with low altitude (LA) native peers in order to explain the nocturnal …

Study Objectives: Physiological adaptation to high altitude hypoxia may be impaired in
Andeans with significant European ancestry. The respiratory ‘burden’ of sleep may challenge …

Background In international studies, greater investment in primary health care is associated
with improved population health outcomes. Aim To determine whether investment in general …

Background Providing high-quality clinical care and good patient experience are priorities
for most healthcare systems. Aim To understand the relationship between general practice …